Text Trish to Book - 404.606.0617

Because Serenity is What We Are All Hoping to Restore
Welcome to Serene Restoration
Compassionate, concierge psychiatric care that puts you at the center
24/7 direct access to your provider for support when you need it most
Individualized treatment plans tailored to your unique goals and challenges
Comprehensive services including:
Medication Management
Addiction Recovery Support
Supportive Therapy
Medical Weight Care
Care Across the Lifespan
Commitment to treating every person with warmth, respect, and dignity
Restorative Services

Integrative Medication Follow Up - 15
Follow-up sessions are designed to provide ongoing support and careful monitoring of your progress. These visits are especially helpful when things are stable and going well, allowing us to check in, confirm that your treatment is working effectively, and make small adjustments if needed.

Crisis Psychotherapy Session
There are times when life feels overwhelming and you simply need a safe space to talk it out. A psychotherapy crisis appointment provides immediate support during those moments.

Initial Psychiatric Evaluation
Your first visit is a 60-minute comprehensive evaluation focused on understanding you as a whole person. We will review your medical and psychiatric history, discuss your goals for treatment, and consider how underlying health conditions may affect your mental well-being.

Integrative Medication Follow Up - 30
These follow-up sessions are designed for times when more in-depth attention is needed. During this visit, we will review your progress in detail, discuss any changes in your symptoms, and make careful adjustments to your medication regimen if appropriate.

Integrative Medication Follow Up - 45
The 45-minute follow-up session is designed for times when you need a more thorough review of your progress and treatment plan. This visit allows us to take a deeper look at how you’re feeling, carefully assess your response to medications, and make thoughtful adjustments when needed.

Integrative Medication Follow up - 60
The 60-minute follow-up session provides the most comprehensive level of ongoing care. This visit is ideal when significant changes in your health, medications, or life circumstances need careful review. With extended time, we can thoroughly assess your progress, evaluate how your treatment plan is working, and make thoughtful adjustments as needed. This longer session ensures there is ample space for detailed discussion, questions, and a deeper focus on overall wellness

Family Consultations
Family consultations provide an opportunity for loved ones to be included in the treatment process when appropriate. With a signed release of information, these sessions allow family members to share valuable collateral information and to participate in a collaborative discussion of the treatment plan.

Military Psychiatric Evaluation - Entry
A military psychiatric evaluation is a comprehensive assessment required for entry into the armed services. This evaluation provides a thorough review of mental health history, current functioning, and fitness for duty to ensure readiness for military service.

Academic Accommodation Referral
For college students managing mental health conditions, academic accommodations can provide essential support in achieving educational success. An academic accommodation referral includes a comprehensive psychiatric review and a detailed written letter documenting the need for accommodations related to a diagnosed mental health condition.

Ketamine Infusion Series Referral
For individuals struggling with treatment-resistant depression, anxiety, OCD, or PTSD, ketamine therapy may offer a new path toward relief. Before beginning treatment, a comprehensive psychiatric evaluation is required to determine eligibility and ensure safety.

Emotional Support Animal Evaluation & Letter
This one-on-one evaluation provides a comprehensive psychiatric assessment by a board-certified PMHNP to determine eligibility for an Emotional Support Animal (ESA) letter. During your private telehealth or in-person session, we explore your mental-health history, current needs, and the therapeutic role your animal plays in your well-being. If clinically appropriate, you’ll receive an official ESA letter on Serene Restoration TLH letterhead, compliant with federal housing and accessibility stand
Meet Trish Allmon
Trish is a Board-Certified Nurse Practitioner in Acute Care & Psychiatric Mental Health. With over 20 years of experience in both Acute Care and Psychiatric Mental Health, Trish is dedicated to helping patients overcome the challenges of treatment-resistant mental illness and addiction.
Her extensive work in emergency psychiatry at Tallahassee Memorial Hospital, combined with her concierge and consulting practice, Serene Restoration, reflects her belief that mental health care should be personalized, accessible, and compassionate.
Trish practices integrative psychiatry, blending the spiritual, mental, and medical aspects of care to support healing of the whole person. She is committed to providing inclusive, affirming care for individuals from all walks of life, including the LGBTQ+ community, ensuring that every patient feels respected, understood, and supported.
Trish provides highly individualized care designed to restore serenity, resilience, and hope—throughout every stage of life.

Passionate about helping individuals overcome the toughest psychiatric challenges with personalized, concierge care.
Trusted Local Partners in Care
Hand-picked clinicians and programs we know, trust, and gladly recommend—so you can get the right help, right away.
Not for emergencies. If you’re in crisis, call 988 or go to the nearest ER.
Healing Reads:
Trusted Books for Mental Wellness
A curated blend of New York Times bestsellers and clinical resources recommended by Serene Restoration.
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🌿 Want to Order From a Trusted Place? When it comes to supplements, quality matters just as much as the ingredient. Many store-bought and Amazon brands are under-dosed, contaminated, or inconsistent — which can make a huge difference in safety and effectiveness. To help my patients access third-party tested, medical-grade supplements, I use Fullscript, a professional wellness dispensary that only carries verified, high-integrity brands. 🛒 Fullscript Ordering (Serene Restoration TLH) If you’d like access to my Fullscript recommendations and discounts: 📧 Email me: trish@serenerestoration.com 📱 Call/Text: 404-606-0617 Once I add you to my Fullscript system, you will get: ✨ 10% off your first order ✨ Access to trusted, clinician-grade supplement brands ✨ Direct communication with me for questions or product swaps ✨ Auto-updates if anything I recommend changes ❓ Can you open a Fullscript account without me adding you? No. Fullscript does not allow patients to open an account on their own. They must be invited by a provider. So if you'd like to order from Fullscript, simply email or text me, and I will create your account and send your discount link. Serene Supplement Spotlight Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains. 🌿💊✨ For questions, guidance, or personalized recommendations: trish@serenerestoration.com | 404-606-0617
Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains.

Cannabidiol (CBD Oil)
🧠 What It Supports
-
Anxiety & stress regulation
-
Sleep onset + quality
-
Physical tension
-
Inflammatory pain
-
Nervous system calming
-
Post-stress recovery
-
Mood stabilization support
⚠️ Possible Side Effects
-
Dry mouth
-
Lightheadedness
-
Fatigue or sedation (higher doses)
-
Appetite changes
-
Loose stools (rare, usually with large doses)
-
Headache (rare; more common with unregulated products)
🚫 Major Interactions & Safety Notes
CBD is metabolized by CYP3A4 and CYP2C19, meaning it can increase levels of many medications.
Use caution or avoid if taking:
-
Benzodiazepines (Xanax, Klonopin, Ativan) — may increase sedation
-
SSRIs / SNRIs / TCAs — potential for increased serum levels
-
Stimulants (Adderall, Vyvanse) — can blunt or unpredictably interact
-
Anticonvulsants (Lamotrigine, Topamax, Oxcarbazepine)
-
Atypical antipsychotics (Latuda, Abilify, Seroquel)
-
Blood thinners (Warfarin)
Not recommended in:
-
Pregnancy / breastfeeding
-
Significant liver impairment
-
People taking multiple CNS depressants
Always talk to me or your prescriber before using CBD with psychiatric meds.
🌱 Recommended Dosage Ranges (General wellness ranges)
-
Low: 10–20 mg
-
Moderate: 20–40 mg
-
Sleep: 30–60 mg
-
Pain: 25–50 mg (varies widely)
Start low. Go slow. Stay consistent.
⭐ Trusted Brands
Fullscript
-
Charlotte’s Web CBD Oil — calm + sleep focused
-
CBDistillery Full-Spectrum Oil — consistent potency
-
HempFusion Stress Relief — broad spectrum
Amazon
(Only choose certified 3rd-party tested products)
-
Medterra CBD Oil (THC-Free) — clean, lab-verified
-
Lazarus Naturals Full-Spectrum — high potency
Always verify COA (certificate of analysis).

L-Carnosine
🧠 What It Supports
Brain fog + cognitive clarity
Mood stability
Neurological health + neuronal protection
Inflammation reduction
Blood sugar support
Cellular aging + oxidative stress reduction
Nervous system “calming” during high stress states
May help reduce irritability or emotional reactivity
⚠️ Possible Side Effects
Most people tolerate carnosine very well. Potential mild effects:Nausea (rare)HeadacheMild stomach upsetRestlessness if taken too late in the day (rare)Taking with food lowers stomach sensitivity.
🚫 Major Interactions & Safety Notes
L-Carnosine is generally low-risk, but caution is advised with:
Stimulants (Adderall, Vyvanse) – may mildly enhance focus → monitor overstimulation
Blood pressure meds – theoretical reduction of BP (monitor)
Diabetes medications – mild blood sugar impact (monitor)Thyroid medications – rare reports of sensitivityAvoid in:
Pregnancy or breastfeeding (insufficient safety data)
Active peptic ulcers if taken on empty stomach
🌿 Recommended Dosage Ranges
General Brain Support: 250–500 mg daily
Cognitive / Mood Support: 500–1,000 mg daily
Anti-glycation / Aging Support: up to 1,000 mg daily
Best taken in the morning or early afternoon.
⭐ Trusted Brands
Fullscript
NOW Foods L-Carnosine 500mg – reliable + cost-effective
Designs for Health L-Carnosine – pharmaceutical-grade
purityPure Encapsulations Carnosine – hypoallergenic + clean formulation
Amazon
Doctor’s Best L-Carnosine – third-party tested
NOW Foods L-Carnosine – consistent lab verification

L- Carnitine
🧠 What It Supports
Energy production + mitochondrial function
Brain fog + cognitive fatigue
Mood support
Nervous system regulation
Healthy metabolism + fat utilization
Muscle recovery
Focus/attention support
➕ Autism-Specific Support
Research has shown potential benefit in kids and adults with autism, including:Improved focusReduced irritabilityBetter overall energy regulationSupport for mitochondrial function, which can be impaired in some ASD individualsThis is not a treatment for autism, but may support neurological and metabolic balance.
🔍 How It Differs from Similar Supplements
✔️ L-Carnitine vs. Acetyl-L-Carnitine (ALCAR)
L-Carnitine:
More metabolic + mitochondrial
Supports energy, muscles, and fatigue
Mild brain benefits
Acetyl-L-Carnitine (ALCAR):
Crosses the blood–brain barrier more easily
Stronger effect on mood, cognition, ADHD, and memory
Many people use both, depending on goals.
✔️ L-Carnitine vs. L-Carnosine
Not the same supplement.
Carnitine = energy + mitochondria
Carnosine = antioxidant + calming + anti-inflammatory
They complement each other but work differently.
⚠️ Possible Side Effects
Most are mild:
Nausea or stomach upsetF
ishy odor (rare; dose dependent)
Restlessness if taken late in the day
Mild headache
Take with food if sensitive.
🚫 Major Interactions & Safety Notes
Use caution with:
Thyroid meds (Levothyroxine): may reduce absorption
Blood thinners: theoretical interactions
Stimulants (Adderall/Vyvanse): may increase energy → monitor for overstimulation
Anticonvulsants: metabolic interactions are low but monitor
Avoid in:Pregnancy/breastfeeding (limited data)
History of seizures if using high doses (rare reports)
🌿 Recommended Dosage Ranges
Energy support: 500–1,000 mg daily
Metabolic support: 1,000–2,000 mg daily
Autism/neurological support: 50–100 mg/kg/day (clinical dosing; only with provider guidance)
Best taken in the morning or midday.
⭐ Trusted Brands
Fullscript
Thorne L-Carnitine – pure, medical-grade
Pure Encapsulations L-Carnitine – hypoallergenic
Designs for Health Carnitine Synergy – high-quality blend
Amazon
Doctor’s Best L-Carnitine Fumarate – third-party tested
NOW L-Carnitine – consistent potency

Chamomile
🧠 What It Supports
-
Anxiety + emotional tension
-
Sleep onset + nighttime calming
-
GI stress (nervous stomach)
-
PMS-related irritability
-
Mild muscle relaxation
-
Nervous-system soothing after overstimulation
-
Gentle mood stabilization support
Chamomile is especially helpful for patients who have “tired but wired” nighttime patterns or anxiety tied to GI discomfort.
⚠️ Possible Side Effects
Chamomile is generally very gentle. Mild effects may include:
-
Drowsiness
-
Nausea (rare)
-
Allergic reactions in people sensitive to ragweed, daisies, chrysanthemums
-
Loose stools (rare, usually with high doses)
Most side effects improve by using standardized extracts rather than random teas.
🚫 Major Interactions & Safety Notes
Use caution with:
-
Benzodiazepines (Xanax, Ativan, Klonopin) → additive sedation
-
Trazodone, Mirtazapine, Seroquel, Hydroxyzine → increased drowsiness
-
Blood thinners (Warfarin) → potential mild increased bleeding risk
-
Sedating antihistamines → stronger drowsiness
Avoid in:
-
Pregnancy unless approved by OB
-
Known ragweed allergy
-
Before driving or tasks requiring concentration
🌿 Recommended Dosage Ranges
-
Tea: 1–2 cups, 30–60 minutes before bed
-
Extract / Capsules: 200–400 mg daily (standardized to apigenin)
-
Liquid tincture: 1–3 droppers at bedtime
For anxiety: smaller daytime doses.
For sleep: slightly higher nighttime doses.
⭐ Trusted Brands
Fullscript
-
Gaia Herbs Chamomile – clean, potent extract
-
Herb Pharm Chamomile Extract – high bioavailability
-
Pure Encapsulations Chamomile – hypoallergenic capsule form
-
Amazon
-
Traditional Medicinals Organic Chamomile Tea – reliable and organic
-
Nature’s Way Chamomile Extract – third-party tested

Chromium
🧠 What It Supports
-
Blood sugar stability
-
Sugar cravings + carb cravings
-
Energy consistency
-
PMS-related mood swings
-
Insulin sensitivity
-
Metabolic support
-
Mood stability in patients with glucose dysregulation
-
Why Trish often recommends it:
Chromium can help patients whose anxiety, irritability, or mood dips are connected to blood sugar swings — especially in PMDD, stress eating, and adrenal fatigue patterns.
⚠️ Possible Side Effects
Chromium is usually well-tolerated. Potential effects include:
-
Mild stomach upset
-
Headache
-
Dizziness (rare)
-
Sleep disturbance if taken late (rare)
High doses >1000 mcg/day may cause:
-
Irritability
-
Kidney strain (rare, with chronic excessive use)
🚫 Major Interactions & Safety Notes
Use caution with:
-
Diabetes medications (metformin, insulin) — may enhance blood sugar lowering
-
Steroids
-
Levothyroxine — separate dosing by 3–4 hours
-
Beta-blockers — mild effect on glucose stability
Avoid if:
-
Kidney disease
-
Severe liver disease
-
Pregnancy without provider guidance
🌿 Recommended Dosage Ranges
-
Cravings / PMS: 200–400 mcg daily
-
Blood sugar support: 200–600 mcg daily
-
Metabolic support: 400–1000 mcg daily
Take with food to avoid nausea.
⭐ Trusted Brands
Fullscript
-
Designs for Health Chromium Synergy
-
Pure Encapsulations Chromium Picolinate
-
NOW Chromium Picolinate
Amazon
-
Doctor’s Best High Absorption Chromium
-
NOW Chromium Picolinate

Citicoline
🧠 What It Supports
-
Focus + attention
-
Executive functioning
-
ADHD support
-
Memory + learning
-
Brain energy + mitochondrial support
-
Mood regulation
-
Stroke recovery / cognitive rehab
-
Neuroprotection (phospholipid support)
⚠️ Possible Side Effects
Usually very well tolerated. Possible:
-
Headache
-
Stomach upset
-
Restlessness (if taken late)
-
Mild increase in heart rate
-
Insomnia at high doses
🚫 Major Interactions & Safety Notes
Use caution with:
-
Stimulants (Adderall, Vyvanse) — may increase focus TOO much → adjust dose
-
Bupropion (Wellbutrin) — additive stimulating effect
-
Modafinil / armodafinil — enhanced wakefulness
-
Blood pressure meds — mild BP reduction possible
Do not use at night — it can activate the brain.
🌿 Recommended Dosage Ranges
-
Cognitive Support: 250–500 mg daily
-
ADHD / Focus: 250–500 mg once or twice daily
-
Brain Recovery: 500–2,000 mg daily (clinical settings)
Best taken morning + early afternoon.
⭐ Trusted Brands
Fullscript
-
CogniPhos by Designs for Health
-
Pure Encapsulations Citicoline
-
Thorne Citicoline
Amazon
-
Jarrow Formulas Citicoline (CDP-Choline)
-
Double Wood Citicoline
Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains.

CocoaVia
🧠 What It Supports
CocoaVia contains high-potency cocoa flavanols, which support:
-
Improved cognitive performance
-
Sharper memory + processing speed
-
Enhanced focus + mental clarity
-
Improved blood flow to the brain
-
Cardiovascular health + circulation
-
Anti-inflammatory + antioxidant protection
-
Healthy nitric oxide signaling
One of the most research-backed flavanol supplements for brain + heart.
⚠️ Possible Side Effects
Generally very well tolerated.
Occasionally:
-
Mild nausea (if taken without food)
-
Headache (rare; usually hydration related)
-
Caffeine sensitivity (very small amount naturally occurring)
-
Loose stools if taking high doses
🚫 Major Interactions & Safety Notes
Use caution with:
-
Blood thinners (Warfarin, Eliquis) – flavanols may mildly enhance blood flow
-
Stimulants – can increase circulation + alertness
-
Blood pressure meds – may mildly lower BP
-
MAO inhibitors – theoretical additive effects
Avoid in:
-
Pregnancy/breastfeeding unless approved by provider
-
Severe liver disease (rare concern but best to clarify)
No issues with SSRIs, SNRIs, TCAs, antipsychotics, or mood stabilizers — generally safe.
🌿 Recommended Dosage Ranges
Evidence-based dosing:
-
200–500 mg cocoa flavanols daily
(Most clinical studies use 500–750 mg)
CocoaVia packages typically deliver:
-
Cardio Health Capsule: 500 mg flavanols/day
-
Brain Health Capsule or Stick Pack: 750 mg/day
Take in the morning or early afternoon for best cognitive effect.
⭐ Trusted Brands
Fullscript
CocoaVia is typically purchased through the brand directly or Amazon; however, similar flavanol products include:
-
Designs for Health Cocoa Luxe
-
NOW Foods Cocoa Flavanols
Amazon
-
CocoaVia™ Cardio Health Capsules
-
CocoaVia™ Memory + Focus Capsules (Brain Health)
-
CocoaVia™ Stick Packs (Cocoa Flavanol Drink Mix)

Gingko (Tebonin)
🧠 What It Supports
-
Cognitive function + memory
-
Tardive-Dyskinesia
-
Age-related cognitive decline; dementia
-
Attention + mental clarity
-
Circulation to the brain
-
Reduction of “brain fog”
-
Mood balance
-
Antioxidant + neuroprotective effects
-
May support age-related cognitive decline
-
Can benefit individuals with ADHD symptoms (mild support)
⚠️ Possible Side Effects
Most are mild but important to note:
-
Headache
-
Stomach upset
-
Dizziness
-
Mild nausea
-
Restlessness or light stimulation (rare)
-
Increased bleeding tendency (important!)
Stop at least 7 days before surgery.
🚫 Major Interactions & Safety Notes
Ginkgo affects platelet function and CYP pathways → use carefully.
Do NOT combine with:
-
Blood thinners: warfarin, Eliquis, Xarelto
-
Antiplatelets: aspirin, Plavix
-
NSAIDs: ibuprofen/naproxen (increases bleeding risk)
-
Seizure medications: may lower seizure threshold
-
SSRIs/SNRIs — theoretical risk of serotonin effects (low, but caution)
Extra caution in:
-
Pregnancy or breastfeeding
-
Anyone with bleeding disorders
-
People prone to migraines
-
History of seizures
🌿 Recommended Dosage Ranges
-
Standard cognitive support: 120–240 mg/day
-
Divided doses morning + afternoon preferred
-
Choose standardized extract 24% flavone glycosides / 6% terpene lactones
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations Ginkgo – clean, hypoallergenic
-
Integrative Therapeutics Ginkgo – standardized, clinically used
-
Vital Nutrients Ginkgo – strong quality control
Amazon
-
NOW Ginkgo Biloba 120 mg – reliable + third-party tested
-
Doctor’s Best Extra Strength Ginkgo – standardized extract
Avoid non-standardized bulk powders.

Coenzyme Q10 (CoQ10)
🧠 What It Supports
-
Cellular energy production (mitochondrial support)
-
Brain fog + cognitive fatigue
-
Mood stability + emotional regulation
-
Heart health + circulation
-
Stress recovery + antioxidant protection
-
Healthy metabolism
-
Physical energy + exercise recovery
Bonus:
CoQ10 is especially helpful for patients with fatigue, statin use, mitochondrial vulnerability, burnout, or those feeling “exhausted but wired.”
⚠️ Possible Side Effects
CoQ10 is very well tolerated. Potential mild effects:
-
Stomach upset or nausea (rare; take with food)
-
Headache
-
Insomnia if taken too late in the day
-
Mild agitation (rare)
🚫 Major Interactions & Safety Notes
Use caution with:
-
Blood thinners (Warfarin/Coumadin) – may reduce effectiveness; monitor INR
-
Blood pressure medications – CoQ10 may mildly lower BP
-
Diabetes medications – may mildly affect glucose
-
Chemotherapy agents – potential interactions; avoid unless oncologist approves
Avoid in:
-
Pregnancy / breastfeeding (insufficient data)
-
Active cardiovascular instability unless medically supervised
🌿 Recommended Dosage Ranges
-
General wellness: 100 mg daily
-
Fatigue or mood support: 100–200 mg daily
-
Statin users: 200 mg daily
-
Severe fatigue / mitochondrial support: 200–300 mg daily
Best taken in the morning or with lunch (stimulating for some people).
Take with fat for best absorption.
⭐ Trusted Brands
Fullscript
-
Thorne CoQ10 – extremely clean, highly absorbable
-
Designs for Health CoQnol Ubiquinol – excellent mitochondrial support
-
Pure Encapsulations Ubiquinol-QH – hypoallergenic, great for sensitive patients
Amazon
-
Qunol Ubiquinol – clinically studied absorption
-
NOW CoQ10 – consistent, third-party verified
💡 Ubiquinone vs. Ubiquinol
-
Ubiquinone: classic form, still effective
-
Ubiquinol: more bioavailable; best for older adults or patients with fatigue

Ginseng
🧠 What It Supports
-
Energy & vitality without stimulant jitters
-
Mental clarity + cognitive performance
-
Focus + productivity (especially when fatigued)
-
Stress resilience / adaptogenic support
-
Immune health
-
Healthy cortisol balance
➕ Sexual Health Benefits
-
Improved libido in men & women
-
Better erectile function
-
Enhanced arousal and sexual satisfaction
-
May support hormonal balance and vitality
⚠️ Possible Side Effects
Typically mild but may include:
-
Headache
-
Insomnia if taken late in the day
-
GI upset
-
Increased heart rate (rare)
-
Restlessness (dose-dependent)
-
Possible acne flare in sensitive individuals
🚫 Major Interactions & Safety Notes
Use caution with:
-
Stimulants (Adderall, Vyvanse, caffeine) → may amplify effects
-
Blood pressure medications (can mildly raise or lower BP unpredictably)
-
Anticoagulants (Warfarin, Eliquis) → may increase bleeding risk
-
Diabetes medications → may lower blood sugar
-
Antidepressants (SSRIs/SNRIs) → theoretical interaction; monitor anxiety
-
MAOIs → contraindicated
Avoid in:
-
Pregnancy (stimulating effects)
-
Uncontrolled hypertension
-
Bipolar disorder with mania risk (may feel activating)
🌿 Recommended Dosage Ranges
-
Energy / Focus: 200–400 mg daily
-
Cognition: 200–300 mg daily
-
Sexual function: 1,000–3,000 mg standardized extract daily (varies by product)
-
Immune support: 200–400 mg daily
Best taken in the morning or early afternoon.
⭐ Trusted Brands
Fullscript
-
Korean Ginseng by Herb Pharm – clean, potent extract
-
Panax Ginseng by Pure Encapsulations – hypoallergenic, reliable
-
Designs for Health Adrenotone – ginseng blend for stress + energy
Amazon
(Choose third-party tested only)
-
Nature’s Answer Panax Ginseng – high quality extract
-
NOW Panax Ginseng – cost-effective + consistent

Creatine
🧠 What It Supports
-
Cognitive performance
-
Memory + mental processing
-
Mood support
-
Energy production (ATP)
-
Muscle recovery
-
Brain health after stress or burnout
-
ADHD support (emerging research)
⚠️ Possible Side Effects
-
Mild bloating
-
Water retention
-
GI upset if taken without water
-
Headache (rare)
Very safe long-term.
🚫 Major Interactions
Creatine is extremely low-interaction.
Use caution only with:
-
Dehydration risks
-
Kidney disease (discuss with provider)
No significant psych med interactions.
🌿 Recommended Dosage
-
Standard: 3–5 g daily
-
Brain support: 5 g daily
-
No loading phase needed
⭐ Trusted Brands
Fullscript: Thorne Creatine
Amazon: Optimum Nutrition Creatine, BulkSupplements Creatine Monohydrate

Inositol
🧠 What It Supports
Inositol is a naturally occurring B-vitamin–like compound that supports:
-
Bipolar depression
-
May help improve depressive symptoms
-
Supports serotonin signaling
-
Often used as an adjunct in mood stabilization
-
-
Fatigue & brain fog
-
Helps stabilize energy through insulin regulation
-
Supports calming neurotransmission
-
-
Bulimia & binge-eating urges
-
Reduces compulsive urges + craving intensity
-
Helps regulate serotonin and insulin responses
-
-
Psoriasis
-
Helps balance immune response
-
Reduces lithium-related psoriasis flares
-
-
Anxiety & OCD symptoms
-
PMDD + menstrual-related mood changes
-
Sleep quality (especially when combined with magnesium)
⚠️ Possible Side Effects
Usually very well tolerated. Possible mild effects:
-
Gas or bloating
-
Loose stools at high doses
-
Sleepiness (large nighttime doses)
-
Headache (rare)
Lower dose if GI upset occurs.
🚫 Major Interactions & Safety Notes
Inositol is generally safe, but consider:
Use caution with:
-
Mood stabilizers (Lithium):
-
May reduce lithium-induced psoriasis (good), but very high doses can alter lithium effectiveness → monitor mood
-
-
SSRIs / SNRIs:
-
Typically safe; monitor for increased serotonergic activity
-
-
Diabetes medications:
-
Inositol improves insulin sensitivity → blood sugar may drop faster
-
Avoid or use only with close oversight in:
-
Type 1 diabetes (needs glucose monitoring)
-
Pregnancy/Breastfeeding: safe in PCOS dosing, but higher psychiatric doses need provider approval
🌿 Recommended Dosage Ranges
Mood + Bipolar Depression:
-
6–12 grams per day (divided 2–3x/day)
Higher therapeutic dosing should be supervised.
Bulimia / Binge Eating / OCD-type urges:
-
12–18 grams per day (divided)
Strongest evidence at higher range.
Psoriasis (esp. lithium-induced):
-
6 grams daily
Fatigue / Energy Balance:
-
2–4 grams daily
General calming / anxiety support:
-
2–6 grams daily
Start low (1–2 g) and increase slowly to reduce GI effects.
⭐ Trusted Brands
Fullscript
-
Jarrow Formulas Inositol Powder – highly pure, easily dosed
-
Designs for Health Inositol – medical-grade powder
-
Pure Encapsulations Inositol – hypoallergenic capsules/powder
Amazon
-
NOW Myo-Inositol Powder – third-party tested
-
Bulk Supplements Inositol – simple, reliable, budget-friendly
Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains.

Lavender (Silexan)
🧠 What It Supports
Lavender is one of the most well-studied natural calming agents.
It supports:
General anxiety (GAD)
Situational anxiety + stress recovery
Sleep onset + improved sleep quality
Restlessness + agitation
Mild depressive symptoms
Somatic tension (heart racing, chest tightness)
Nervous system down-regulation
Pain and headache relief via muscle relaxation
Silexan® (oral lavender oil) has the strongest clinical research for anxiety and sleep.
⚠️ Possible Side Effects
Lavender is well tolerated.
Potential effects include:
Mild GI upset
Headache (rare)
Slight sedation
Skin irritation only if applied topically (essential oil must be diluted)
Oral lavender does NOT cause hormonal effects at typical doses despite myths from topical essential oils.
🚫 Major Interactions & Safety Notes
Sedative medications (benzodiazepines, trazodone, hydroxyzine): may increase calming effects
CNS depressants: additive sedationAnticoagulants: very mild theoretical interaction (rarely clinically significant)
SSRIs/SNRIs: no direct contraindication—generally considered safe
Topical essential oil: can irritate skin if not diluted with carrier oil
Avoid or use caution in:
Pregnancy/breastfeeding (limited oral data)
Those with severe asthma triggered by fragrances
🌿 Recommended Dosage Ranges
Oral (Silexan/Lavender Oil Capsules): 80 mg once daily (most studied for GAD)160 mg daily for severe anxiety or sleep onset difficulty
Aromatherapy: 2–4 drops in diffuser1–2 drops on cotton ball near bedside1 drop on wrists or behind ears (if diluted)
Topical:Use only when diluted: 1–2% dilution in carrier oil
⭐ Trusted Brands
Fullscript
Integrative Therapeutics Lavela (Silexan 80 mg) – gold standard for anxiety
Gaia Herbs Lavender
NOW Essential Oils Lavender (aromatherapy)
Amazon
Integrative Therapeutics Lavela (Silexan 80 mg)
Plant Therapy Lavender Essential Oil (quality-tested)
Edens Garden Lavender Oil
For educational purposes only. Always consult your provider before combining lavender supplements with other calming medications.

Lemon Balm
🧠 What It Supports
-
Anxiety + nervous irritability
-
Sleep initiation + restlessness
-
Stress-related GI upset
-
Mild depression symptoms
-
Cognitive calm + focus
-
PMS/PMDD mood instability
-
Somatic tension (neck, shoulders, jaw)
-
Known as a “gentle nervine,” ideal for anxious rumination and stress-related physical symptoms.
⚠️ Possible Side Effects
-
Drowsiness (especially with high doses)
-
Nausea
-
Headache
-
Rare paradoxical agitation (in very sensitive individuals)
🚫 Major Interactions & Safety Notes
-
Sedatives / sleep meds (trazodone, mirtazapine, benzodiazepines) — additive effect
-
Thyroid medications — may mildly inhibit TSH; monitor
-
Stimulants — may soften overstimulation
-
Avoid during pregnancy/breastfeeding without provider guidance
-
Caution in hypothyroidism (mild TSH suppression possible)
🌿 Recommended Dosage Ranges
-
Anxiety / Calming: 300–600 mg up to 2× daily
-
Sleep: 300–500 mg 30–60 min before bed
-
Tea: 1–2 tsp dried herb steeped 10 minutes
⭐ Trusted Brands
Fullscript
-
Gaia Herbs Lemon Balm
-
Integrative Therapeutics Kava/Lemon Balm blends
-
Herb Pharm Lemon Balm Extract
Amazon
-
Nature’s Way Lemon Balm 500mg
-
Gaia Lemon Balm Liquid Phyto-Caps

Melatonin
🧠 What It Supports
-
Sleep onset (falling asleep)
-
Circadian rhythm regulation
-
Shift-work sleep issues
-
Jet lag recovery
-
Nighttime anxiety/restlessness
-
REM sleep support
-
Antioxidant + neuroprotective effects
➕ Neurological Benefits
-
May help reduce symptoms of tardive dyskinesia (TD)
Melatonin’s antioxidant + mitochondrial protective effects have shown benefit in reducing TD severity in some studies. -
Supports memory + cognitive aging
Melatonin may improve REM cycles, reduce oxidative brain stress, and support long-term memory processing.
⚠️ Possible Side Effects
-
Morning grogginess
-
Vivid dreams
-
Headache
-
Mood irritability in some
-
Lower libido (with high doses)
-
Daytime sleepiness if dose is too strong
-
May worsen depression in a minority of sensitive individuals
🚫 Major Interactions & Safety Notes
Use caution with:
-
Sedatives / sleep meds (Ambien, trazodone, benzodiazepines)
-
Antidepressants (SSRIs/SNRIs) — may increase sedation
-
Blood pressure meds — may lower BP further
-
Immunosuppressants — melatonin can stimulate immune activity
-
Anticoagulants (blood thinners)
Not recommended for:
-
People with autoimmune disorders (unless cleared)
-
Pregnancy / breastfeeding
-
Severe depression with hypersomnia
Melatonin can paradoxically worsen sleep in some (especially if dose is too high).
🌿 Recommended Dosage Ranges
-
Sleep onset: 0.5–3 mg nightly
-
Insomnia: 1–5 mg nightly
-
Tardive Dyskinesia support: 5–10 mg (provider-guided only)
-
Cognitive support: 1–3 mg
Important: More is not better. Start at 0.5–1 mg and only increase as needed.
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations Melatonin – hypoallergenic, clean
-
Designs for Health Melatonin – pharmaceutical-grade
-
Douglas Labs Melatonin – consistent potency
Amazon
-
Life Extension Melatonin – highly reputable
-
Natrol Melatonin – fast-dissolve option
Educational only — consult your provider before combining melatonin with psychiatric medications or using higher doses for neurological conditions.

l-Methylfolate
🧠 What It Supports
-
Depression (especially when antidepressants are only partially effective)
-
Treatment-resistant depression
-
MTHFR gene variants that impair folate conversion
-
Neurotransmitter synthesis (serotonin, dopamine, norepinephrine)
-
Autism spectrum support (folate-dependent pathways)
-
Fatigue + low motivation
-
Prenatal and cellular health
-
Memory + cognitive performance
🌱 Why It Helps Depression
L-Methylfolate crosses the blood–brain barrier and directly increases the production of:
-
Serotonin
-
Dopamine
-
Norepinephrine
-
This makes antidepressants work better, especially in individuals with:
-
MTHFR C677T or A1298C variants
-
Chronic low folate levels
-
Treatment resistance
-
It is commonly used as an adjunct to SSRIs/SNRIs.
🌈 Autism Support Notes
Preliminary research suggests L-methylfolate may support:
-
Methylation pathways
-
Folate-dependent neurological function
-
Behavior regulation
-
Cognitive development
-
Not a primary treatment for autism — used as a supportive metabolic nutrient.
🧬 MTHFR Genetic Variant Support
-
If someone has an MTHFR mutation, they may not convert standard folic acid into its active form. L-methylfolate bypasses that block, delivering the form the brain actually uses.
Benefits may include:
-
Better mood stability
-
Improved energy
-
Fewer side effects from high folic acid intake
-
Better medication response
⚠️ Possible Side Effects
-
Usually very well tolerated.
Mild possibilities: -
Anxiety or activation (if dose too high)
-
Insomnia if taken late
-
Headache
-
GI upset (rare)
-
If overstimulating: decrease dose.
🚫 Major Interactions & Safety Notes
Use caution or avoid with:
-
High-dose SSRIs/SNRIs — can increase neurotransmitter activity
-
Bipolar disorder — may trigger activation at high doses
-
Folic acid supplements — unnecessary duplication
-
Anticonvulsants (Tegretol, Depakote) — can affect folate metabolism
-
Safe in low doses during pregnancy, but always discuss with a provider.
🌿 Recommended Dosage Ranges
-
General mood support: 1–5 mg daily
-
MTHFR support: 1–5 mg daily
-
Adjunct for antidepressants: 7.5–15 mg daily (prescription formulations)
-
Autism support: typically lower conservative doses (0.5–2 mg)
-
Start low. Increase slowly.
⭐ Trusted Brands
Fullscript
-
Metabolic Maintenance L-Methylfolate
-
Designs for Health 5-MTHF
-
Pure Encapsulations L-Methylfolate (hypoallergenic)
Amazon
-
Solgar Metafolin (5-MTHF)
-
Jarrow Methyl Folate
-
Doctor’s Best Fully Active Folate
Avoid any product labeled only “folic acid.”

Lithium Orate
🧠 What It Supports
Lithium orotate is a low-dose, over-the-counter mineral form of lithium that may support:
-
Mood stability
-
Emotional regulation
-
Irritability reduction
-
Impulsive thinking
-
Racing thoughts
-
Anxiety reduction
-
Sleep regulation
➕ Cognitive & Dementia Prevention Benefits
Low-dose lithium has been studied for its potential to:
-
Support long-term brain health
-
Reduce risk of cognitive decline
-
Help protect against dementia (dose-dependent; low-dose appears beneficial)
-
Stabilize neuronal mitochondrial function
-
Support neuroplasticity
These effects are specific to very low doses — not higher doses.
⚠️ Very Important Safety Notes
⭐ Lithium orotate is NOT the same as prescription lithium (Lithium Carbonate)
-
It absorbs differently
-
It concentrates more heavily inside cells
-
It can cause toxicity at much lower doses than prescription versions
⭐ High doses are dangerous
-
Even though OTC, lithium orotate can cause toxicity faster than prescription lithium
-
Do NOT exceed the low-dose amounts sold commercially (typically 5mg elemental lithium)
-
Do not take multiple tablets
-
Do not combine with OTC lithium from different brands
❗ DO NOT USE if taking prescription lithium
They are not interchangeable and combining them is dangerous.
⚠️ Possible Side Effects
Even at low doses, some people may experience:
-
Nausea
-
Increased thirst
-
Increased urination
-
Brain fog
-
Headache
-
Tremor
-
Restlessness or fatigue
-
Thyroid sensitivity (rare but possible)
-
Mood flattening (if dose too high)
Stop immediately if symptoms occur.
🚫 Major Interactions & Contraindications
Use caution or avoid if taking:
-
Diuretics (Lasix, HCTZ) — raises lithium levels
-
NSAIDs (Ibuprofen, Naproxen) — increases toxicity risk
-
ACE inhibitors/ARBs (Lisinopril, Losartan) — raises lithium concentrations
-
Antipsychotics (Seroquel, Abilify, Latuda) — potential destabilization
-
Kidney medications or kidney disease
-
Thyroid disease
Avoid in:
-
Pregnancy
-
Breastfeeding
-
Significant renal or thyroid issues
-
Any patient already on prescription bipolar medications unless coordinated with your provider
🌿 Recommended Dosage Ranges (ONLY low dose)
-
Standard low dose: 5 mg elemental lithium daily (common OTC pill strength)
-
Do NOT exceed: 10 mg elemental lithium/day
-
Best taken: at night with food
Higher doses dramatically increase risk of toxicity and should never be taken without medical supervision.
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations Lithium (Orotate) 5 mg — highly trusted, clean
-
Advanced Research Lithium Orotate — long-standing formulation
Amazon
(Choose only brands with clear elemental lithium labeling)
-
Pure Encapsulations Lithium (Orotate)
-
Seeking Health Lithium Orotate

N-Acetylcysteine (NAC)
🧠 What It Supports
NAC is one of the most evidence-supported supplements in psychiatry and neurology.
Mental Health Benefits
-
Depression – improves glutathione, reduces neuroinflammation
-
Bipolar Disorder – reduces depressive episodes and emotional volatility
-
Addiction Recovery – supports cravings reduction (nicotine, cannabis, opioids, alcohol)
-
Autism (ASD) – reduces irritability, meltdowns, and repetitive behaviors
-
Schizophrenia – may help negative symptoms (motivation, emotional flatness)
Medical / Whole-Body Benefits
-
Renal (Kidney) Support – protects kidneys from oxidative stress
-
Liver Detox Pathway Support
-
Respiratory health – breaks down mucus; supports chronic respiratory conditions
-
Anti-inflammatory + antioxidant action across multiple systems
⚠️ Possible Side Effects
Mostly mild:
-
Nausea
-
GI upset or gas
-
Headache
-
Fatigue (rare)
-
Possible sulfur-like odor
Less common:
-
Mild lowering of blood pressure
-
Rare allergic reactions in sensitive individuals
🚫 Major Interactions & Safety Notes
Use with caution if taking:
-
Nitroglycerin – may cause severe headaches + BP drops
-
Blood thinners (Warfarin) – may enhance effects
-
Activated charcoal – decreases absorption
-
Certain chemo meds (check with oncology)
Avoid or consult provider if:
-
You have asthma (may increase bronchospasm in rare cases)
-
You have an active bleeding disorder
-
Pregnant/breastfeeding (insufficient safety data)
NAC is generally very safe, but dosing should be tailored.
💊 Recommended Dosage Ranges
-
Depression / Bipolar: 1,200–2,400 mg/day
-
Addictions / OCD behaviors: 1,200–3,000 mg/day
-
Autism irritability: 900–2,700 mg/day
-
Kidney/Liver support: 600–1,800 mg/day
Take with food to reduce nausea.
⭐ Trusted Brands
Fullscript
-
Thorne NAC – clean, highly bioavailable
-
Pure Encapsulations NAC – hypoallergenic
-
Designs for Health NAC – professional grade
Amazon
-
NOW NAC 600 mg – third-party tested
-
Jarrow NAC – consistent quality
Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains.

l-Lysine
🧠 What It Supports
-
Anxiety reduction
-
Cortisol regulation + stress buffering
-
Improved stress tolerance during high-pressure periods
-
Enhanced immune function
-
Skin + collagen health
-
Cognitive support in schizophrenia (paired with antipsychotic treatment)
-
May improve some negative or cognitive symptoms in schizophrenia
-
Reduction in herpes simplex recurrence
🔍 Special Mental Health Benefits
✔️ Anxiety Support
L-Lysine can help:
-
Decrease anxiety by modulating serotonin receptors
-
Reduce physiological stress responses
-
Lower cortisol levels during acute stress conditions
-
Improve sleep indirectly by reducing anxiety
Clinical trials show meaningful decreases in trait and state anxiety when taken consistently.
✔️ Schizophrenia Support (Adjunct to medication)
Research suggests L-Lysine may improve cognition and some negative symptoms by:
-
Modulating glutamate pathways
-
Supporting neuronal signaling
-
Enhancing overall stress resilience
It is not a standalone treatment, but may help enhance clarity, attention, and processing speed in some patients.
⚠️ Possible Side Effects
Generally well tolerated.
Possible mild effects:
-
Stomach upset
-
Nausea
-
Bloating
-
Rarely—gallstone risk with extremely high doses over long periods
-
Headache (rare)
Take with food to reduce GI sensitivity.
🚫 Major Interactions & Safety Notes
Use caution with:
-
High-dose calcium supplementation (may increase absorption to excess)
-
Kidney disease — avoid unless medically supervised
-
Severe liver disease — metabolized through amino pathways
-
Pregnancy/breastfeeding — insufficient data for high doses
No major psychiatric medication interactions are known.
🌿 Recommended Dosage Ranges
-
General wellness / stress support: 500–1,000 mg daily
-
Anxiety / cortisol reduction: 1,000–3,000 mg daily
-
Adjunct for schizophrenia cognition: 2,000–4,000 mg daily (only under provider supervision)
-
Herpes/immune support: 1,000 mg once or twice daily
Best taken in divided doses if using more than 1,000 mg/day.
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations L-Lysine – clean, hypoallergenic
-
Designs for Health L-Lysine – clinical-grade
-
NOW Foods L-Lysine 500mg – reliable and affordable
Amazon
-
Doctor’s Best L-Lysine
-
NOW L-Lysine 1,000 mg


Magnesium
🧠 What It Supports
-
Insomnia + sleep quality (especially when combined with melatonin)
-
Anxiety + muscle tension
-
Nervous system calming
-
Stress resilience + mood regulation
-
Restless sleep / nighttime agitation
-
Bruxism (teeth grinding)
-
Tics / Tourette’s symptoms
-
Liver support in alcohol use disorder
-
Constipation relief (depending on form)
🔬 How It Helps
• Insomnia (especially with Melatonin)
Magnesium activates GABA receptors, reduces muscle tension, and helps the brain shift into parasympathetic mode.
Combo with melatonin improves sleep onset + maintenance.
• Bruxism (Teeth Grinding)
Low magnesium increases neuromuscular excitability → supplementation reduces jaw tension + grinding frequency.
• Tourette’s / Tics
Helps stabilize neuromuscular firing and reduce tic frequency in some individuals.
• Liver Health in Alcohol Use Disorder
Chronic alcohol use depletes magnesium, contributing to neuropathy, arrhythmias, and liver stress.
Repletion improves liver enzyme regulation and mitochondrial function.
⚠️ Possible Side Effects
-
Loose stools (more common with citrate or oxide)
-
Stomach cramping
-
Low blood pressure (rare)
-
Drowsiness (nighttime forms like glycinate)
Highly dependent on the form used.
🚫 Major Interactions & Safety Notes
Use caution with:
-
Sedatives → may intensify calming/drowsiness
-
Antibiotics (tetracyclines, quinolones) → magnesium lowers absorption
-
Blood pressure meds → may enhance lowering effect
-
Heart block or severe kidney impairment → avoid unless medically supervised
Safe with most psychiatric medications.
🌿 Best Forms for Mental Health
-
Magnesium Glycinate → calm, sleep, anxiety
-
Magnesium L-Threonate → cognition + brain absorption
-
Magnesium Taurate → mood + cardiovascular calm
-
Magnesium Citrate → helpful if constipation is present
Avoid magnesium oxide—poor absorption.
⭐ Recommended Dosage Ranges
-
General calm + sleep: 200–400 mg nightly
-
Tics / neuromuscular support: 200–400 mg/day
-
Bruxism: 250–350 mg at night
-
Alcohol use disorder: 200–400 mg/day (with provider oversight)
Start low. Increase slowly.
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations Magnesium Glycinate
-
Designs for Health Magnesium Buffered Chelate
-
Thorne Magnesium Bisglycinate
Amazon
-
Doctor’s Best High Absorption Magnesium Glycinate
-
NOW Magnesium Glycinate


Omega-3 (Fish Oil)
🧠 What It Supports
Omega-3s are one of the most well-studied, brain-protective, anti-inflammatory nutrients available.
Benefits include:
Mood & Psychiatric Conditions
-
Depression (especially EPA-dominant formulas 1,000–2,000 mg/day)
-
Bipolar disorder (helps depressive episodes + irritability)
-
Borderline Personality Disorder (emotional regulation, reduced impulsivity)
-
ADHD (improves focus, impulse control, and processing speed)
-
Autism spectrum (supports cognition, irritability, and inflammation)
Metabolic & Physical Health
-
Cholesterol improvements (raises HDL, lowers triglycerides)
-
Blood pressure support (HTN)
-
Reduced systemic inflammation
-
Skin health (psoriasis, eczema, acne)
-
Joint & cardiovascular support
Behavioral & Neurological Regulation
-
Reduced irritability, agitation, and explosive episodes
-
Supports cognitive function, memory, and brain resilience
⚠️ Possible Side Effects
-
Mild nausea
-
Fishy aftertaste or burping
-
Loose stools
-
Headache (rare)
-
Easy bruising at very high doses
Taking with meals reduces symptoms.
🚫 Major Interactions & Safety Notes
Use caution with:
-
Blood thinners (Coumadin/Warfarin, Eliquis, Xarelto)
-
High-dose aspirin or NSAIDs
-
Pre-operative periods (stop 1–2 weeks before surgery unless otherwise directed)
Generally safe in pregnancy, breastfeeding, and adolescents.
🌿 Recommended Dosage Ranges
-
General health: 1,000 mg EPA+DHA
-
Depression: 1,000–2,000 mg EPA-dominant
-
ADHD / ASD: 1,000–1,500 mg combined
-
Cardiovascular / triglycerides: 2,000–4,000 mg/day
-
Skin/psoriasis: 2,000–3,000 mg/day
Look for “triglyceride form” or “re-esterified triglyceride” for best absorption.
⭐ Trusted Brands
Fullscript
-
Nordic Naturals ProOmega – high EPA/DHA, top-tier purity
-
Designs for Health OmegAvail – triglyceride form, excellent absorption
-
Carlson Labs Fish Oil – pharmaceutical-grade
Amazon
(Choose only 3rd-party tested products)
-
Viva Naturals Triple-Strength Omega-3
-
Sports Research Omega-3 (rTG form)
-
Nordic Naturals (official Amazon store)

PEA (palmitoylethanolamide)
Phosphatidylserine (PS)
Probiotics
🧠 What It Supports
PEA is a naturally occurring fatty acid amide that calms neuroinflammation and supports cellular repair.
Clinically Noted Benefits:
-
Depression (reduces neuroinflammation contributing to mood symptoms)
-
Bipolar Disorder
-
May reduce mania, agitation, and inflammatory-driven mood cycling
-
-
Long COVID
-
Improved fatigue, body pain, cognition, and inflammatory symptoms
-
-
Chronic Pain
-
Neuropathic pain
-
Fibromyalgia
-
Arthritis pain
-
-
Migraines
-
Helps headaches linked to mast cell activation or inflammation
-
🧬 Additional Emerging Research
🧠 Dementia / Cognitive Decline
-
Combination therapy under study for Frontotemporal Dementia (FTD):
-
PEA: 700 mg BID
-
Luteoline: 70 mg BID
-
-
Early results show improved cognition, behavior, and neuroinflammation.
This is not a cure, but research is promising for slowing decline.
⚠️ Brand Note (Important)
LEVEGEN PEA
-
Clinically tested, highly pure, medical-grade form
-
Often provides stronger symptom improvement
-
More expensive than standard OTC versions
You can list:
-
Levagen+ PEA
-
Doctor’s Best PEA (Levagen-based)
⚠️ Possible Side Effects
PEA is extremely well tolerated. Rare/mild:
-
Stomach discomfort
-
Bloating
-
Headache (rare)
-
Fatigue if dosed too high
Most people report zero negative effects.
🚫 Major Interactions & Safety Notes
-
No major medication interactions identified
-
Safe with antidepressants, stimulants, mood stabilizers
-
Avoid in pregnancy (insufficient data)
-
Use caution if taking immunosuppressive drugs
-
Stop 7 days before surgery (theoretical platelet effects)
🌿 Recommended Dosage Ranges
-
General mood support: 300–600 mg daily
-
Pain / migraines: 600–1,200 mg daily
-
Bipolar mania support: 600–1,200 mg
-
Long COVID: 600 mg BID
-
FTD / dementia combo:
-
PEA 700 mg BID
-
Luteoline 70 mg BID (provider-guided only)
-
Best taken with food.
⭐ Trusted Brands
Fullscript
-
Designs for Health PEA Synergy
-
Pure Encapsulations PEA
-
LEVAGEN PEA formulations (highest quality)
Amazon
-
Doctor’s Best PEA (Levagen+)
-
NOW PEA
-
Toniiq Ultra High Purity PEA
🧠 What It Supports
-
Attention + focus (ADHD)
-
Working memory
-
Information processing speed
-
Cognitive stamina
-
Stress resilience (lowers cortisol)
-
Age-related memory decline
-
Executive function + task initiation
ADHD-Specific Support
Multiple studies show that PS improves attention, impulsivity, and hyperactivity, especially when combined with Omega-3 fatty acids, typically DHA.
Improvements noted in:
-
Sustained attention
-
Behavioral regulation
-
Processing speed
-
Mood + irritability stability
-
School/work performance
⚠️ Possible Side Effects
Rare and very mild:
-
Stomach upset
-
Insomnia if taken later in the evening
-
Headache (uncommon)
Take with food if sensitive.
🚫 Major Interactions & Safety Notes
Generally very safe, but:
-
Avoid taking after 3pm → may increase alertness
-
Monitor if taking stimulants (Adderall, Vyvanse) → can potentiate focus
-
Blood thinners (theoretical interaction; caution with high doses)
Safe for most people, including long-term use.
Avoid if:
-
Pregnant/breastfeeding (limited research)
🌿 Recommended Dosage Ranges
-
ADHD Support: 200–300 mg per day
-
Memory Support: 100–200 mg per day
-
Stress Regulation: 100 mg per day
Most studies used 200–300 mg daily + Omega-3 DHA for ADHD.
⭐ Trusted Brands
Fullscript
-
Jarrow Formulas PS100 – stable, reliable
-
Designs for Health Phosphatidylserine – premium, pure
-
Pure Encapsulations Phosphatidylserine – hypoallergenic
Amazon
-
Double Wood Phosphatidylserine – third-party tested
-
NOW Phosphatidyl Serine – consistent potency
Phosphatidylserine is for educational purposes only. Always consult your provider before combining with ADHD medication.
🧠 What They Support
Research continues to confirm the powerful gut–brain connection. Probiotics may help with:
-
Depression (improved mood, reduced inflammation)
-
Anxiety (supports serotonin + GABA production)
-
Stress tolerance
-
Cognitive clarity + focus
-
Sleep regulation (improves circadian rhythm signals from the gut)
-
ADHD symptoms (via inflammation and gut microbiome balance)
-
Autism-related symptoms (GI discomfort, irritability, social engagement)
-
GI symptoms that worsen mood – bloating, constipation, IBS
-
Immune function (gut = 70% of immune system)
Strains matter → certain strains affect mood, others digestion, others inflammation.
⚠️ Possible Side Effects
Usually mild and temporary—especially in the first 1–2 weeks:
-
Gas or bloating
-
Mild stomach cramping
-
Temporary loose stools or constipation
-
Increased thirst
-
Rare: nausea
If severe symptoms occur, reduce dose or switch strains.
🚫 Major Interactions & Safety Notes
Probiotics are generally very safe.
Use caution or avoid if:
-
You are immunocompromised
-
You have a central venous catheter
-
You are on immunosuppressant therapy
-
You have SIBO → may worsen symptoms
-
You have short-gut syndrome or severe GI illness
Medication Interactions:
-
Antibiotics may reduce effectiveness — space doses 2–3 hours apart
-
Rare reports of interaction with chemotherapy agents
-
No major psychiatric medication interactions
🌿 Recommended Dosage & Types
Varies by symptom:
Mood / Anxiety / Depression:
-
10–20 billion CFU
-
Look for strains: Lactobacillus helveticus, Bifidobacterium longum
Irritability / Autism GI Support:
-
Multi-strain blends with Bifidobacterium infantis, B. breve
Cognitive Support:
-
Combinations with prebiotics (FOS, GOS)
-
Synbiotics preferred
General Gut Support:
-
10–50 billion CFU multi-strain
Take daily with food.
⭐ Trusted Brands
Fullscript
-
Metagenics UltraFlora – strain-specific mental health blends
-
Klaire Labs Ther-Biotic – clean, hypoallergenic, diverse strains
-
Designs for Health ProbioMed – high-potency clinical strains
Amazon
(Choose only 3rd-party tested products)
-
Garden of Life Mood+ Probiotics – targeted for stress + mood
-
Culturelle Pro-Well – evidence-backed strains
-
Align Probiotic – stable strain with strong GI support
Probiotics are strain-specific -- always consult your provider to match strains to your symptoms.
Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains.

Resveratrol
🧠 What It Supports
-
ADHD: may improve cognitive flexibility, working memory, and attention through antioxidant + anti-inflammatory effects
-
Heart health: supports endothelial function, circulation, and healthy blood pressure
-
Anti-aging: promotes cellular repair, mitochondrial health, and longevity pathways (SIRT1 activation)
-
Reduces oxidative stress + inflammation
-
Supports metabolic wellness and healthy cholesterol levels
-
Neuroprotective benefits for long-term brain health
⚠️ Possible Side Effects
Most people tolerate it well. Mild effects may include:
-
Headache
-
Digestive upset
-
Loose stools (at higher doses)
-
Dry mouth
-
Mild dizziness (rare)
Take with food if sensitive.
🚫 Major Interactions & Safety Notes
Use caution with:
-
Blood thinners (Warfarin, Eliquis) — may increase bleeding risk
-
NSAIDs — additive blood-thinning effects
-
Estrogen medications — phytoestrogen activity (monitor)
-
Antihypertensives — may mildly lower BP
-
Diabetes medications — may lower blood sugar
Avoid in:
-
Pregnancy / breastfeeding
-
Upcoming surgery (stop 2 weeks prior)
🌿 Recommended Dosage Ranges
-
General wellness: 100–150 mg/day
-
Heart health + metabolic support: 150–300 mg/day
-
Cognitive/ADHD support: 150–300 mg/day
-
Anti-aging focus: 200–500 mg/day
Best taken in the morning with food.
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations Resveratrol VESIsorb – highly bioavailable
-
Designs for Health Resveratrol Supreme – potent + clean formulation
-
Integrative Therapeutics Resveratrol Ultra – standardized dose
Amazon
-
NOW Natural Resveratrol – third-party tested
-
Toniiq Resveratrol – high purity, lab validated
Resveratrol is for educational purposes only — always consult your provider when combining supplements with medication.

Rhodiola Rosea
🧠 What It Supports
Rhodiola is an adaptogenic herb that helps the body regulate stress hormones and improve physical and mental resilience.
-
Anxiety
-
Depression
-
Concentration + cognitive performance
-
Fatigue (mental + physical)
-
Sleep problems related to stress dysregulation
-
Burnout + emotional exhaustion
-
Stress coping capacity
-
Mood stability in periods of overload
Many patients feel calmer + more energized without sedation.
⚠️ Possible Side Effects
Generally well tolerated. Potential effects include:
-
Mild stimulation or restlessness if taken late in the day
-
Dry mouth
-
Headache
-
Dizziness (rare)
-
Upset stomach (rare)
-
Temporary vivid dreams (uncommon)
Avoid taking after 3 PM due to mild energizing effect.
🚫 Major Interactions & Safety Notes
Use caution with:
-
Stimulants (Adderall, Vyvanse): may increase stimulation
-
SSRIs/SNRIs: theoretical serotonin interaction—monitor
-
Bipolar disorder: rare activation risk → start low
-
Benzodiazepines: may lower sedative effect slightly
-
Sedative meds: mild wakefulness effect may require spacing doses
Avoid in:
-
Pregnancy / breastfeeding
-
Severe uncontrolled anxiety until stabilized (start low)
🌿 Recommended Dosage Ranges
-
Stress + anxiety: 100–200 mg daily
-
Fatigue / cognition: 200–400 mg daily
-
Burnout support: 200–300 mg in the morning
Important: Choose standardized extract (3% rosavins, 1% salidroside).
⭐ Trusted Brands
Fullscript
-
Gaia Herbs Rhodiola Rosea – strong purity & adaptogen blend
-
Integrative Therapeutics Rhodiola – clinically studied dose
-
Designs for Health Rhodiola Supreme – potent + clean
Amazon
-
NOW Rhodiola Rosea – third-party tested
-
NutraChamps Rhodiola – consistent potency
resilience”
For educational use only. Always consult your provider before combining Rhodiola with psychiatric medications.

Saffron
🧠 What It Supports
Clinically one of the best studied natural mood enhancers.
Benefits include:
-
Depression (mild–moderate) — comparable to SSRIs in several studies
-
Anxiety reduction
-
ADHD — supports attention, focus, and emotional regulation (often used alongside stimulants)
-
OCD — mild anti-obsessive effects
-
Sleep improvement — calming + serotonin effects
-
Menopause symptoms — mood, irritability, vasomotor symptoms
-
Sexual dysfunction — improves low libido + SSRI-related sexual side effects
⚠️ Possible Side Effects
Generally well-tolerated. Potential mild effects include:
-
Nausea
-
Headache
-
Sleepiness (if dosed at night—can also help sleep)
-
Dry mouth
-
Mood elevation → (monitor in bipolar disorder)
-
Yellow-orange sweat or urine (harmless)
High doses (>400 mg/day) can be unsafe → stick to standardized supplement doses.
🚫 Major Interactions & Safety Notes
Use caution with:
-
SSRIs/SNRIs/TCAs → theoretical additive serotonin effect
-
Bipolar disorder → may rarely trigger hypomania; monitor
-
Blood thinners → possible mild anticoagulant effect
-
Pregnancy → avoid high doses (traditional use suggests uterine stimulation)
Do NOT use culinary saffron as a substitute for standardized supplements.
🌿 Recommended Dosage Ranges
Common clinical dosing:
-
28–30 mg daily (standardized extract, most researched)
-
60 mg daily for depression, ADHD, OCD
-
15 mg twice daily for mood + sexual function
Consistency is key — allow 4–6 weeks for full effect.
⭐ Trusted Brands
Fullscript
-
Integrative Therapeutics Saffron (high purity)
-
Pure Encapsulations Saffron
-
Designs for Health NeuroCalm + Saffron blends
Amazon (look for 3rd-party tested)
-
Life Extension Optimized Saffron
-
Nutrabay / iHerb Verified Brands
-
Educational only — consult your provider before combining saffron with psychiatric medications.



Sarcosine
SAM-e (S-Adenosyl-L-Methionine)
St. Johns Wort
🧠 What It Supports
-
Depression (adjunctive support)
-
Schizophrenia — especially negative symptoms
-
Apathy
-
Low motivation
-
Cognitive slowing
-
Social withdrawal
-
-
Cognitive function (processing speed, attention, working memory)
-
Mood regulation
-
Glutamate system support (NMDA modulation)
Sarcosine works on the glycine transporter-1 (GlyT1), which enhances NMDA receptor activity — a completely different pathway from SSRIs or dopamine-targeting antipsychotics.
⚠️ Possible Side Effects
Usually well tolerated. Possible mild effects:
-
Nausea
-
Stomach discomfort
-
Headache
-
Restlessness or activation (dose-related)
-
Insomnia if taken too late in the day
🚫 Major Interactions & Safety Notes
Use caution with:
-
Antipsychotics, especially Clozapine — may increase activation
-
Glutamate-modulating meds (ketamine, memantine) — theoretical interaction
-
Stimulants — may increase alertness
-
MAOIs — not recommended together
Avoid in:
-
Pregnancy/breastfeeding
-
Uncontrolled bipolar mania (may increase activation)
🌿 Recommended Dosage Ranges
-
Depression: 1–2 grams daily
-
Schizophrenia (negative symptoms): 2 grams daily (studies commonly use this dose)
-
Take morning or split AM/PM
-
Avoid taking close to bedtime
⭐ Trusted Brands
Fullscript
-
Serenity Nutrition Sarcosine Powder – pure, lab-tested
-
Doctor’s Best Sarcosine – consistent research-grade quality
Amazon
-
Cognitive Nutrition Sarcosine Powder – third-party tested
-
Double Wood Sarcosine – reliable purity + clear COA
Educational use only. Always consult your provider before adding sarcosine to antipsychotic or mood treatment plans.
🧠 What It Supports
-
Depression (robust evidence; similar effect size to some SSRIs)
-
Anxiety reduction
-
Improved sexual function (especially antidepressant-related dysfunction)
-
Parkinson’s support (mood + motor adjunct)
-
Arthritis + joint pain
-
Fibromyalgia
-
Liver health (supports methylation + detox pathways)
-
Overall cellular methylation (important for neurotransmitter production)
⚠️ IMPORTANT STABILITY WARNING
SAM-e is a very fragile compound.
✔️ Only buy enteric-coated capsules
✔️ Products must be individually blister-packed
✔️ Exposure to air or moisture will degrade SAM-e and make it ineffective
✔️ Avoid bulk bottles — potency will be lost after opening
⚠️ Possible Side Effects
-
Nausea
-
Stomach upset
-
Restlessness
-
Headache
-
Sweating or jitteriness (dose-related)
-
Insomnia if taken late in the day
Take in the morning with food.
🚫 Major Interactions & Safety Notes
SAM-e increases serotonin and must be used cautiously with:
-
SSRIs, SNRIs (risk of serotonin excess)
-
MAOIs (unsafe combination)
-
Tricyclic antidepressants
-
Trazodone
-
Stimulants (may increase jitteriness)
-
Bipolar Disorder: may trigger mania or hypomania — monitor closely
Avoid in:
-
Pregnancy/breastfeeding
-
Active mania or cycling bipolar
-
Uncontrolled anxiety/panic unless carefully supervised
🌿 Recommended Dosage Ranges
-
Mood support: 200–400 mg daily
-
Depression: 400–1,600 mg daily (divided doses)
-
Joint pain: 600–1,200 mg daily
-
Liver support: 400–800 mg daily
Start low → increase slowly over 1–2 weeks.
⭐ Trusted Brands
Must be enteric-coated + blister-pack only
Fullscript
-
Jarrow Formulas SAM-e (high stability, blister-packed)
-
Doctor’s Best SAM-e (pharmaceutical grade)
-
Life Extension SAM-e (enteric + blister pack)
Amazon
(Only choose blister-packed versions from reputable manufacturers)
-
Jarrow SAM-e 200 or 400mg
-
Doctor’s Best SAM-e
Educational use only. SAM-e should be used cautiously with antidepressants and always under provider supervision.
🧠 What It Supports
-
Mild to moderate depression
-
Mood stabilization support
-
Emotional resilience
-
Nervous system calming
-
Seasonal mood concerns
Most evidence is for mild–moderate depressive symptoms.
⚠️ CRITICAL WARNINGS (Must Be Prominently Displayed)
🚫 1. Most St. John’s Wort products do NOT have good integrity
-
Potency varies dramatically
-
Many brands fail purity testing
-
Active compounds (hypericin & hyperforin) are inconsistent
🚫 2. Dangerous in Bipolar Disorder
-
Can trigger mania, hypomania, or rapid cycling
-
Not safe for bipolar depression
-
Should never be taken without provider supervision
🚫 3. Major, Dangerous Drug Interactions
St. John’s Wort induces CYP3A4, CYP2C9, CYP2C19, and P-glycoprotein, causing dramatic drops in medication levels.
May reduce or alter levels of:
-
SSRIs, SNRIs, TCAs, MAOIs
-
Antipsychotics (Latuda, Seroquel, Abilify)
-
Benzodiazepines
-
Birth control pills → can cause contraceptive failure
-
Blood thinners (warfarin)
-
Immunosuppressants
-
HIV medications
-
Chemotherapy drugs
-
Transplant medications
-
Opioids
-
Migraine medications (triptans)
NEVER COMBINE with SSRIs, SNRIs, or MAOIs → risk of serotonin syndrome.
🚫 4. NOT safe in pregnancy or breastfeeding.
🌿 Possible Side Effects
-
Sun sensitivity (photosensitivity)
-
Anxiety or insomnia
-
Headache
-
Dry mouth
-
Dizziness
-
GI upset
-
Increased sweating
🌱 Recommended Dosage (If Used With Provider Oversight Only)
-
Typical range: 300 mg standardized extract (0.3% hypericin) 2–3× daily
-
Extended-release options available
Only use standardized, third-party tested products.
⭐ Trusted Brands (Fullscript Only — avoid Amazon)
Because most OTC brands fail testing, only use validated options:
-
Gaia Herbs St. John’s Wort
-
Integrative Therapeutics St. John’s Wort
-
MediHerb St. John’s Wort
High-risk supplement with major interactions.
Use ONLY under medical supervision.
Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains.

l-Theanine
🧠 What It Supports
-
Depression – may enhance alpha-wave activity → improved calm focus and mood
-
Anxiety & stress – reduces physiological stress response
-
Insomnia – improves sleep quality by calming the nervous system
-
Attention & focus – especially when paired with small amounts of caffeine
-
Emotional regulation
-
Irritability
This supplement is ideal for people who feel “wired but tired,” overthinking, or overstimulated.
⚠️ Possible Side Effects
Generally very well tolerated.
-
Headache (rare)
-
Mild GI upset
-
Lower blood pressure (monitor if hypotensive)
-
Sleepiness at higher doses
Most people experience calm focus rather than sedation.
🚫 Major Interactions & Safety Notes
-
Blood pressure medications – may mildly enhance effects
-
Stimulants (Adderall, Vyvanse) – can smooth jitters and comedowns; monitor response
-
Sedating meds (benzodiazepines, trazodone, hydroxyzine) – may enhance calming effect
-
SSRIs/SNRIs – low interaction risk; generally safe
Avoid or use caution in:
-
Pregnancy / breastfeeding (insufficient research)
-
People with very low blood pressure
-
🌿 Recommended Dosage Ranges
-
General Calm: 100–200 mg once or twice daily
-
Acute Anxiety / Stress: 200–400 mg
-
Sleep: 200–400 mg 30–60 minutes before bed
-
Focus (with caffeine): 100–200 mg paired with 25–100 mg caffeine
Works within 30–60 minutes; can be used situationally or daily.
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations L-Theanine – clean, hypoallergenic
-
Integrative Therapeutics L-Theanine – high quality
-
NOW L-Theanine Double Strength
Amazon
-
Suntheanine® (Doctor’s Best) – the most researched, patented form
-
NOW L-Theanine – consistent and verified
This information is educational only. Always consult your provider before adding L-theanine, especially with psychiatric medications.

Valerian
🧠 What It Supports
-
Insomnia – helps with sleep onset & calming nighttime restlessness
-
Anxiety – reduces physical tension + worry loops
-
OCD – may lessen obsessive thought intensity through GABA modulation
-
Sleep maintenance (fewer nighttime awakenings)
-
Nervous system relaxation
-
Stress recovery after overstimulation
⚠️ Possible Side Effects
Most are mild and dose-related:
-
Morning grogginess if taken too late
-
Headache
-
Stomach upset
-
Vivid dreams
-
Dizziness (rare)
-
“Herbal” smell that some people dislike
Avoid alcohol with valerian due to additive sedation.
🚫 Major Interactions & Safety Notes
Valerian acts on the GABA system, so use caution with:
-
Benzodiazepines (Xanax, Ativan, Klonopin)
-
Sleep medications (Ambien, Lunesta)
-
SSRIs/SNRIs – low interaction risk, but additive sedation possible
-
Mood stabilizers – monitor sedation
-
Barbiturates
-
Alcohol – do NOT combine (sedation + confusion risks)
Avoid in:
-
Pregnancy or breastfeeding
-
Before driving or operating heavy machinery
Long-term high doses can cause mild dependence-like effects (rare but reported).
🌿 Recommended Dosage Ranges
-
Sleep support: 400–900 mg, 30–60 minutes before bed
-
Anxiety/stress: 200–400 mg up to twice daily
-
OCD/anxiety blend: Use standardized extract (0.8% valerenic acid)
May take 1–2 weeks of consistent use for full effect.
⭐ Trusted Brands
Fullscript
-
Gaia Herbs Valerian Root – high-potency, clean extraction
-
Integrative Therapeutics Valerian – standardized extract
-
Herb Pharm Valerian Extract – liquid, fast onset
Amazon
-
Nature’s Way Valerian Root – third-party tested
-
NOW Valerian Extract – consistent, reliable dosing
For educational purposes only. Consult your provider before combining valerian with sedatives or psychiatric medications.

Zinc
🧠 What It Supports
-
Depression (especially when paired with antidepressants)
-
Insomnia (helps regulate neurotransmitters tied to sleep)
-
Anorexia / appetite support
-
Immune health
-
Skin healing (acne, rashes, wounds)
-
Hormonal balance
-
Reduction in inflammation
-
Cognitive clarity + stress recovery
Zinc plays a major role in serotonin signaling, glutamate balance, and neuroplasticity, which is why low levels are strongly linked to mood disorders.
⚠️ Possible Side Effects
Usually mild, especially at proper doses:
-
Nausea (most common — avoid on an empty stomach)
-
Stomach upset
-
Metallic taste
-
Headache
-
Copper deficiency if overused long-term
🚫 Major Interactions & Safety Notes
Use caution with:
-
Antibiotics (tetracyclines, quinolones) — reduced absorption
-
Thyroid meds — take zinc 4 hours apart
-
Copper deficiency risk if taking high zinc (>40 mg/day) chronically
Avoid chronic high doses — aim for short-term support unless labs indicate deficiency.
Avoid in:
-
Severe kidney disease (monitor levels)
-
People already on high-dose multivitamins with zinc
💊 Recommended Dosage Ranges
-
General mood / sleep support: 15–25 mg daily
-
Depression adjunct: 25 mg daily (used in clinical trials)
-
Anorexia / appetite support: 15–25 mg daily
-
Short-term immune boost: 30–50 mg daily for 3–7 days only
Best taken with food.
⭐ Trusted Brands
Fullscript
-
Pure Encapsulations Zinc Picolinate 15mg – gentle + reliable
-
Designs for Health Zinc Supreme – includes copper for balance
-
Thorne Zinc Picolinate – highly absorbable
Amazon
-
NOW Zinc Picolinate – inexpensive + third-party tested
-
Garden of Life Vitamin Code Raw Zinc – food-based formula
Educational only. Avoid high doses without provider guidance, especially if taking antibiotics or thyroid medication.


Products with Liver Risks
Antidotes for Side Effects
Some over-the-counter supplements can stress the liver, especially in high doses, poor-quality products, or when combined with other medications.
Liver specialists consider the following supplements to carry some of the highest risk of liver toxicity:
-
Turmeric / Curcumin (high-concentrate extracts)
-
Green tea extracts (concentrated EGCG)
-
Ashwagandha
-
Kratom
-
Garcinia cambogia
-
Red yeast rice
-
Black cohosh
-
Important: It isn’t always clear whether liver injury comes from the core ingredient itself or from contamination, adulterants, or very high/concentrated doses in certain products. Quality and dosing matter.
🌿 Mental Health–Adjacent High-Risk Supplements
Two of these have mental health benefits, but still need extra caution because of possible liver risks:
1️⃣ Ashwagandha
(Withania somnifera; Sensoril®, KSM-66, etc.)
How it may help mental health:
-
Can support stress resilience and anxiety reduction
-
May help with mild depression symptoms in some people
-
Can support sleep quality and overall nervous system calming
-
Adaptogen: may help the body tolerate stress better over time
Liver caution:
-
There are case reports of liver injury in some users.
-
It’s unclear whether the problem is:
-
the herb itself,
-
contamination,
-
very high doses, or
-
interactions with other medications.
-
-
Anyone with known liver disease, heavy alcohol use, or multiple medications should be especially cautious and talk with a provider before using ashwagandha.
2️⃣ Turmeric / Curcumin
(Curcuma longa; curcumin extracts)
How it may help mental health / brain health:
-
Curcumin has anti-inflammatory and antioxidant properties
-
Early research suggests potential benefits for:
-
Depression (as an adjunct)
-
Cognitive health and brain aging
-
General inflammation and pain, which can indirectly affect mood and functioning
-
Liver caution:
-
Most concern is around high-dose, concentrated curcumin extracts, not culinary turmeric used in food.
-
Reported liver injuries may be related to:
-
High doses,
-
Product quality, or
-
Additives/contaminants in some formulations.
-
-
People with liver disease, heavy alcohol use, or who take other potentially hepatotoxic drugs should use curcumin only under medical guidance.
⚠️ General Liver Safety Tips
-
Avoid stacking multiple “strong” supplements at once without medical guidance.
-
If you have a history of liver issues, alcohol use disorder, or are on hepatotoxic medications, always clear supplements with your prescriber.
-
Watch for warning signs: fatigue, dark urine, yellowing of eyes/skin, right upper abdominal pain, nausea → seek medical evaluation.
-
Choose products that are:
-
Third-party tested
-
From reputable brands
-
Transparent with Certificates of Analysis (COAs)
-
Evidence-informed options to reduce common psychiatric medication side effects—educational only, not medical advice.
🔸 Vitamin B6 (Pyridoxine)
Helps with:
-
Tremor
-
Restlessness / Akathisia
-
Antipsychotic-induced prolactin elevation
-
Tardive dyskinesia (TD) support
How it works:
B6 acts as a cofactor for neurotransmitter synthesis and can reduce abnormal movement pathways triggered by dopamine-blocking medications.
Typical dosing: 100–200 mg/day
(Do NOT exceed 200 mg/day long-term — risk of neuropathy.)
🔸 Constipation Relief
Common with: antipsychotics, antidepressants, stimulants, supplements, iron, opioids
Natural antidotes:
-
Magnesium citrate or glycinate
-
Vitamin C (1–2 grams/day)
-
Fiber blends: psyllium, inulin, flax
-
Aloe vera juice (gentle stimulant)
-
Probiotics (gut motility support)
Lifestyle: hydration, movement, warm fluids.
🔸 Nausea Relief
Often from: SSRIs, SNRIs, mood stabilizers, supplements, NAC, omega-3s, SAM-e
Options:
-
Ginger extract (Zingiber officinale)
-
Peppermint oil capsules
-
Vitamin B6 (25 mg with meals)
-
Take meds with food
-
Switch to slower-release formula (provider dependent)
🔸 Dry Mouth (Xerostomia)
Common from: antidepressants, stimulants, antihistamines, benzodiazepines, antipsychotics
Natural antidotes:
-
Xylitol gum or lozenges
-
Biotene mouth spray or gel
-
Aloe vera mouth rinse
-
Fish oil (omega-3) supports mucous membranes
-
Hydration + humidifier at night
🔸 Drooling (Sialorrhea)
Most common with: clozapine, sometimes other antipsychotics
Natural strategies:
-
Atropine 1% drops (off-label, under provider care)
-
Glycopyrrolate (Rx)
-
Chewing xylitol gum
-
Sleeping on the side or with head elevated
There are no effective OTC supplements — this one usually requires medical management.
🔸 Tardive Dyskinesia (TD)
Natural support (adjunct only):
-
Vitamin B6 (100–200 mg/day)
-
Vitamin E (800–1,200 IU/day)
-
N-Acetylcysteine (NAC)
-
Omega-3 fatty acids
-
Melatonin (3–10 mg nightly)
Important:
This does not replace VMAT2 inhibitors (Ingrezza, Austedo), which remain first-line.
These strategies are educational only and do not replace medical guidance. Always consult your prescriber before adding supplements or adjusting medication plans.
Curated with care. Backed by science. Designed to support your calm, clarity, and confidence — because even baddies deserve balanced brains.
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404-606-0617 cellular
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